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Metformin (brand name Glucophage) is the most commonly prescribed drug in the world for the treatment of type 2 diabetes. Because metformin effectively lowers both blood glucose and blood insulin levels, it also reduces the risk to many other chronic degenerative diseases. Consequently, in addition to its use in the treatment of type 2 diabetes, metformin is now becoming recognized as a therapy to slow down aging.
In 2016 the FDA made an unprecedented announcement when it approved a study to examine the effect of metformin on the biology of aging in humans. This study is titled Targeting Aging with Metformin, or the TAME study. This is the first time in history that the FDA has approved any human clinical trial with a goal of establishing a drug’s ability to protect against multiple diseases of aging. In previous studies with different species of animals, therapy with metformin has resulted in significant increases in lifespan. Many healthy people are now electing to take metformin for its ability to slow down aging processes and increase longevity. I want to explain how metformin works so you will understand why it produces so many additional health benefits beyond treating type 2 diabetes.Read more